- U.S. National Bureau of Standards Collection of Computer Literature (2)
- Ukrainian American Collection (101)
- Ukrainian Famine Survivors in Minnesota Oral History Project (11)
- Ukrainian Folk Ballet of the Twin Cities (16)
- Union Settlement records (12)
- United Neighborhood Houses of New York Records (193)
- United Service Organizations-related Records (177)
- United States Department of Agriculture Important Farmlands Maps (582)
- United States Geological Survey Polar Maps (569)
- United States Veterans Administration Social Work Service Records (1)
- United States Youth Council Records (29)
- United Way of Minneapolis Records (64)
- University Relations Records (2)
- University of Minnesota Archives Audio Collection (5127)
- University of Minnesota Archives Photograph Collection (20990)
- University of Minnesota Archives Scrapbook Collection (1)
- University of Minnesota Archives Video Collection (158)
- University of Minnesota Athletics Records (2)
- University of Minnesota Crookston Video Collection (2)
- University of Minnesota Duluth General Historic Photograph Collection (230)