Cortical spreading depression (SD) is a spreading disruption in brain ionic homeostasis during which neurons experience complete and prolonged depolarizations. We perform simulations with a model of SD treating brain tissue as a triphasic continuum of neurons, glia and the extracellular space. A thermodynamically consistent incorporation of the ...
O'Connell, Rosemary (University of Minnesota, Twin Cities)
University of Minnesota, Institute for Mathematics and its Applications.