Globally the energy landscape of a folding protein resembles a partially rough funnel. The local roughness of the funnel reflects transient trapping of the protein configurations in local free energy minima. The overall funnel shape of the landscape, superimposed on this roughness, arises because the interactions present in the native structure ...
Creator:
Onuchic, José Nelson (University of California, San Diego)
Created:
2008-01-17
Contributed By:
University of Minnesota, Institute for Mathematics and its Applications.