Selectivity is one of the most important properties of living systems. One of the founders of molecular biology (Nobel Laureate Aaron Klug) recently said (with some hyperbole I suspect) 'There is only one word that matters in biology and that is specificity.' My collaborators and I study selectivity in ion channels. Ion channels are proteins wit...
Creator:
Eisenberg, Robert S. (Rush University Medical Center)
Created:
2008-12-11
Contributed By:
University of Minnesota, Institute for Mathematics and its Applications.
Biology occurs in concentrated mixtures of ions that are far from ideal. Solutions are remarkably concentrated where they are most important. Multi-molar solutions (often >10M) are found in and near DNA & RNA, proteins, active sites of enzymes, transporters, and ion channels, as well as electrodes of batteries. Poisson Boltzmann treatments fail ...
Creator:
Eisenberg, Robert S. (Rush University)
Created:
2015-07-21
Contributed By:
University of Minnesota, Institute for Mathematics and its Applications.